High-fat feeding is a research area that focuses on studying the effects of a diet high in fat on various aspects of health and metabolism. This type of feeding intervention is often used in animal studies to mimic the typical Western diet, which is characterized by high levels of saturated fat and calories. Research in high-fat feeding often examines the impact of this diet on conditions such as obesity, insulin resistance, diabetes, cardiovascular disease, and inflammation. Studies may investigate how high-fat feeding alters metabolism, hormone levels, gut microbiota composition, and gene expression in different tissues. Overall, high-fat feeding research provides insights into the mechanisms by which a high-fat diet can contribute to the development of chronic diseases and may help to inform dietary recommendations and interventions for improving health outcomes.